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DMXAA accelerates orthodontic tooth movement via macrophage-mediated Rab13-enriched extracellular vesicle release and chemokine secretion

Crossref DOI link: https://doi.org/10.1186/s40510-026-00635-0

Published Online: 2026-06-29

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wang, Yan

Zhang, Kejia

Sun, Xueyu

Xu, Hao

Gu, Heng

Jin, Zhichun

Zhu, Linlin

Zhang, Hanwen

Yan, Bin https://orcid.org/0000-0001-9169-4615
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82371000, 82571135)

Jiangsu Province Capability Improvement Project through the Science, Technology and Education Jiangsu Provincial Research Hospital Cultivation Unit (YJXYYJSDW4)

Jiangsu Provincial Medical Innovation Center (CXZX202227)
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Text and Data Mining valid from 2026-06-29

Version of Record valid from 2026-06-29
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Article History

Received: 21 January 2026

Accepted: 19 June 2026

First Online: 29 June 2026

Change Date: 8 July 2026

Change Type: Update

Change Details: The equal contribution statement on the title page contained an error in the original publication, this article has been updated.

Declarations

:

: C57BL/6 J mice, 8 weeks old, used in this study were obtained from the Laboratory Animal Center of Nanjing Medical University. All mice were maintained in the SPF Medical Experimental Animal Center of Nanjing Medical University, China. All aspects of the animal care and experimental protocols were approved by the Committee of Nanjing Medical University for Animal Resources (approval ID: IACUC‐1601118). This study was reported in accordance with the ARRIVE guidelines 2.0.

: All authors have read and agreed with the submission of the manuscript. This manuscript has not been published or presented elsewhere in part or in entirety.

: The authors declare no competing interests.

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