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Authors
Baysan, M. https://orcid.org/0000-0002-8642-4802
Hilderink, B. https://orcid.org/0000-0001-7684-6529
van Manen, L. https://orcid.org/0000-0001-6777-7875
Caram-Deelder, C. https://orcid.org/0000-0003-3161-5684
Mik, E. G.
Juffermans, N. P. https://orcid.org/0000-0002-3039-6574
van der Bom, J. G. https://orcid.org/0000-0001-9095-2475
Arbous, M. S. https://orcid.org/0000-0001-5242-3257
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Clinical Trials BETA
Clinical trials referenced in this document:
nct03092297 at ClinicalTrials.govDocuments that mention this clinical trial
Study protocol and pilot results of an observational cohort study evaluating effect of red blood cell transfusion on oxygenation and mitochondrial oxygen tension in critically ill patients with anaemia: the INsufficient Oxygenation in the Intensive Care Unit (INOX ICU-2) study (Pre-results)
https://doi.org/10.1136/bmjopen-2019-036351
Mitochondrial oxygen tension in critically ill patients receiving red blood cell transfusions: a multicenter observational cohort study
https://doi.org/10.1186/s40635-024-00646-3
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Funding
Funding for this research was provided by:
Stichting Sanquin Bloedvoorziening (PPOC-16-31)
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Article History
Received: 12 December 2023
Accepted: 26 June 2024
First Online: 8 July 2024
Declarations
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: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the Bioethics Committee of the Medical University of Leiden, the Hague and Delft (P16.303).
: Informed consent was obtained from all individual participants included in the study. However, in case of patients not able to consent, informed consent was obtained from their legal representatives. From February 2019 onwards, deferred consent procedure was used during the study due to logistical problems regarding informed consent for inclusion.
: EG Mik is founder and shareholder of Photonic Healthcare. NP Juffermans is editor-in-chief for <i>Intensive Care Medicine Experimental</i>. The other authors have no conflicts of interest to declare.
