Lyhne, Mads Dam https://orcid.org/0000-0001-5279-260X
Gopalasingam, Nigopan
Berg-Hansen, Kristoffer
Dragsbaek, Simone Juel
Homilius, Casper
Seefeldt, Jacob
Hansen, Jacob Valentin
Kramer, Anders Dahl
Christensen, Lasse Juul
Ellegaard, Mark Stoltenberg
Hørsdal, Oskar Kjærgaard
Overgaard, Andreas
Larsen, Alexander Møller
Boedtkjer, Ebbe
Andersen, Asger
Nielsen, Roni
Funding for this research was provided by:
Oda og Hans Svenningsens Fond
Karen Elise Jensens Fond
National Heart, Lung, and Blood Institute (1R01HL168040-01)
Novo Nordisk Fonden (NNF21OC0071822)
Hjerteforeningen
Article History
Received: 25 September 2025
Accepted: 9 December 2025
First Online: 20 December 2025
Declarations
:
: All institutional and national guidelines for the care and use of laboratory animals were followed and approved by the Danish Animal Experiments Inspectorate (license no. 2021-15-0201-00944). No human studies were carried out by the authors for this article.
: Not applicable.
: AA declares teaching for Gore and Jannssen, and consulting for Inari. RN and JS declare to hold a European patent—application 20205938.2 A Lactate/Ketone Body ester, 5-11-2020. The remaining authors have no conflicts of interest.