He, Hongli
Sugita, Shinji
Hao, Qi
Hwang, Wonjung
Zhou, Li
Naito, Yoshifumi
Shimizu, Masaru
Mukherjee, Sandip
Matthay, Michael A.
Lee, Jae-Woo https://orcid.org/0009-0004-9236-9960
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (140026)
National Heart, Lung, and Blood Institute (134828)
National Heart, Lung, and Blood Institute (113022)
National Heart, Lung, and Blood Institute (148781)
Postdoctoral Research Foundation of China (201808510056)
Article History
Received: 24 November 2025
Accepted: 10 April 2026
First Online: 29 April 2026
Declarations
:
: We obtained de-identified human donor lungs from the Northern Transplant Donor Network (San Ramon, CA) and One Legacy Transplantation Donor Network (Azusa, CA) not used for clinical transplantation. Because the donors are from deceased individuals, the research lungs are not considered human subject research and does not require a separate IRB approval. UCLA and UCSF IRB approval has been obtained for the collection of human blood from healthy donors for the perfusion of human lungs as well as for the isolation of monocytes and neutrophils for in vitro experiments.
: N/A.
: None declared.