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Manuka honey enhanced sensitivity of HepG2, hepatocellular carcinoma cells, for Doxorubicin and induced apoptosis through inhibition of Wnt/β-catenin and ERK1/2

Crossref DOI link: https://doi.org/10.1186/s40659-021-00339-1

Published Online: 2021-05-28

Published Print: 2021-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Al Refaey, Heba R.

Newairy, Al-Sayeda A.

Wahby, Mayssaa M.

Albanese, Chris

Elkewedi, Mohamed

Choudhry, Muhammad Umer

Sultan, Ahmed S. https://orcid.org/0000-0001-6568-1757
Funding

Funding for this research was provided by:

Alexandria University
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Article History

Received: 27 September 2020

Accepted: 3 May 2021

First Online: 28 May 2021

Declarations

:

: Primary human normal neonatal liver cultures (PHNL) were established at Georgetown University, using the conditional reprogramming (CR). All collected tissue samples and the research protocols were performed in accordance with the Institutional Review Board and approved by the ethical committee of GU Hospital and GU Medical Center, USA (Protocol’s No. MOD00001211).

: Not applicable.

: The authors declare that they have no competing interests, financial or otherwise.

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