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Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradation

Crossref DOI link: https://doi.org/10.1186/s40659-023-00413-w

Published Online: 2023-01-23

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Li, Ning

Zhou, Qianyin

Yi, Zhang

Zhang, Huan

Zhou, Dai http://orcid.org/0000-0003-4577-8898
Funding

Funding for this research was provided by:

National Science Fund for Distinguished Young Scholars (82201771)

Natural Science Foundation of Changsha (kq2202491)

Research Grant of CITIC-Xiangya (YNXM 202109)

Research Grant of CITIC-Xiangya (YNXM 202115)

Hunan Provincial Grant for Innovative Province Construction (2019SK4012)
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Text and Data Mining valid from 2023-01-23

Version of Record valid from 2023-01-23
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Article History

Received: 5 July 2022

Accepted: 9 January 2023

First Online: 23 January 2023

Declarations

:

: The Ethical Committee of the Reproductive & Genetic Hospital of CITIC-Xiangya, Basic Medical Science School, Central South University, approved this study (LL-SC-2021–025). All participants were required to sign informed consent. Twenty patients (5 OA and 15 NOA) between the ages of 25 and 46 who underwent microdissection testicular sperm extraction (m-TESE) provided approximately 20 mg of testicular tissues for this study.

: All the authors consent to publish this manuscript.

: The authors declare that they have no competing interests.

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