de Noronha, Sylvana I. S. Rendeiro
de Moraes, Lauro Angelo Gonçalves
Hassell, James E. Jr.
Stamper, Christopher E.
Arnold, Mathew R.
Heinze, Jared D.
Foxx, Christine L.
Lieb, Margaret M.
Cler, Kristin E.
Karns, Bree L.
Jaekel, Sophia
Loupy, Kelsey M.
Silva, Fernanda C. S.
Chianca-, Deoclécio Alves
Lowry, Christopher A.
de Menezes, Rodrigo Cunha http://orcid.org/0000-0003-0286-0621
Funding for this research was provided by:
Conselho Nacional de Desenvolvimento Científico e Tecnológico (Conselho Nacional de Desenvolvimento Científico e Tecnológico)
Fundação de Amparo à Pesquisa do Estado de Minas Gerais (APQ-00359-21, APQ-02182-17, APQ-00823-21, Center of Animal Science (APQ-02511-22))
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Financial Code 001 and the Programa de Doutorado Sanduíche no Exterior [PDSE], process #88881.132957/2016-01)
Financiadora de Estudos e Projetos (Financiadora de Estudos e Projetos)
Universidade Federal de Ouro Preto (Universidade Federal de Ouro Preto)
Foundation for the National Institutes of Health (Foundation for the National Institutes of Health)
National Science Foundation (National Science Foundation)
Institute for Cannabis Research (Institute for Cannabis Research)
Article History
Received: 26 October 2023
Accepted: 23 April 2024
First Online: 6 May 2024
Declarations
:
: C.A.L. is Cofounder, Board Member, and Chief Scientific Officer of Mycobacteria Therapeutics Corporation, and is a member of the faculty of the Integrative Psychiatry Institute, Boulder, Colorado, the Institute for Brain Potential, Los Banos, California, and Intelligent Health Ltd, Reading, UK. All other authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
: Male Wistar rats weighing 100 ± 10 g (5–6 weeks old) were provided by the Center of Animal Science from the Federal University of Ouro Preto (CCA/UFOP). During the experiment, animals were kept in the maintenance facility annex to the Cardiovascular Physiology Laboratory. Animals were kept under a light/dark cycle of 12:12 h (lights on at 6 am), controlled temperature (23 ± 1 ºC), and controlled noise (60–80 dB) with free access to food and tap water. All procedures were approved by the Institutional Animal Care and Use Committee (CEUA#2015/16) and performed according to the regulations set forth by the National Institutes of Health <i>Guide for the Care and Use of Laboratory Animals</i>, and the National Council for the Control of Animal Experimentation (CONCEA).
: Not applicable.