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Authors
Xiang, Yijian
Xu, Yao
Zhang, Jing
Zhu, Miao
He, Zhaowanyue
Zang, Ming
Ma, Rujun
Chen, Li
Li, Zhou
Du, Tian
Yao, Liangyu
Liang, Kuan
Shen, Jiaming
Zhao, Shanmeizi
Jing, Jun
Ge, Xie
Yao, Bing
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (U22A20277)
Jiangsu Provincial Medical Key Discipline Cultivation Unit (JSDW202215)
Postgraduate Research & Practice Innovation Program of Jiangsu Province (KYCX23_1946)
National Key Research and Development Program of China (2024YFC2706800)
the Jiangsu Funding Program for Excellent Postdoctoral Talent (2024ZB593)
the 2024 Annual Science and Technology Innovation Research Program Project of Nanjing Jinling Hospital (2024JCYJQN115)
Independent Research Project of State Key Laboratory of Reproductive Medicine (SKLRM-2022D3)
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Article History
Received: 4 September 2025
Accepted: 27 November 2025
First Online: 17 December 2025
Declarations
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: The protocol of in vivo experiments was approved by the Animal Care and Use Committee of the Jingling Hospital and carried out in accordance with the regular relevant guidelines and regulations (file number 2023JLHGZRDWLS-000129). All procedures were conducted in accordance with the ARRIVE guidelines 2.0 to ensure scientificity, reproducibility, and ethical compliance of preclinical research. Specifically, we implemented randomization, blinding during outcome assessment, and predefined exclusion criteria, as detailed in the Methods section.
: Not applicable.
: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
