Hu, Yuan-Yuan
Pang, Ming-Min
Wang, Hao-Yu
Li, Wen-Xiong
Wang, Hao https://orcid.org/0000-0003-4493-3147
Funding for this research was provided by:
National Natural Science Foundation of China (grant nos. 82072231)
Natural Science Foundation of Shandong Province (ZR2023YQ068)
Taishan Scholar Foundation of Shandong Province (tsqn202103165)
Article History
Received: 20 June 2025
Accepted: 28 September 2025
First Online: 23 October 2025
Declarations
:
: The use of human data in this study was approved by the institutional review boards of the Massachusetts Institute of Technology and Beth Israel Deaconess Medical Center, as well as the ethics committee of Qilu Hospital of Shandong University (2021145). All procedures were conducted in accordance with applicable institutional guidelines and national regulations. The requirement for written informed consent was waived in both cohorts, as the data used were de-identified and complied with ethical and legal standards for anonymized research.
: Not applicable.
: The authors declare that they have no competing interests.