Ueda, Ayami
Furugen, Ayako
Nishimura, Ayako
Umazume, Takeshi
Aoyagi, Ryoichi
Okamoto, Keisuke
Narumi, Katsuya
Ueda, Hinata
Kobayashi, Masaki
Funding for this research was provided by:
Japan Society for the Promotion of Science (24K0237504)
KOSE Cosmetology Research Foundation
Article History
Received: 11 November 2025
Accepted: 29 December 2025
First Online: 24 January 2026
Declarations
:
: This study was approved by the Ethics Committee of the Hokkaido University Hospital (020–0139). Written informed consent was obtained from the participant. This study was performed in accordance with the Declaration of Helsinki and the ethical guidelines for clinical research in Japan.
: Not applicable.
: Ayako Furugen is affiliated with a laboratory supported by Sato Pharmaceutical Co., Ltd.; however, this laboratory was not involved in this study. The other authors declare no conflicts of interest.