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A randomised controlled trial of short-term Intermittent Energy Restriction [IER] versus Continuous Energy Restriction [CER] on body fat stores and measures of insulin resistance in women with obesity at increased risk of breast cancer

Crossref DOI link: https://doi.org/10.1186/s40795-025-01181-4

Published Online: 2025-10-27

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Harvie, Michelle

Coe, Pete

Higham, Claire

Peach, Nina

Howell, Anthony

Evans, D. Gareth

Williams, Stephen

Sellers, Kath

Malcomson, Lee

Pegington, Mary

Renehan, Andrew G.
Funding

Funding for this research was provided by:

NIHR Manchester Biomedical Research Centre (NIHR203308)

prevent breast cancer (GA14-003, GA14-003, GA14-003, GA14-003)

Pancreatic Cancer UK (A16887, A16887)
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Text and Data Mining valid from 2025-10-27

Version of Record valid from 2025-10-27
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Article History

Received: 22 April 2025

Accepted: 25 September 2025

First Online: 27 October 2025

Declarations

:

: The Trial was performed in accordance with the ethical principals in the Declaration of Helsinki was granted ethics approval by the Uk Health Research Authority, National Research Ethics Service Committee South Central-Oxford B [ref14/SC/1097). The trial registration number is ISRCTN10803394, registration date 12/1/2015) ( ). Informed consent was obtained from all subjects involved in the study.

: Not applicable.

: The authors declare no competing interests.

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