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A protocol for a randomised double-blind placebo-controlled feasibility study to determine whether the daily consumption of flavonoid-rich pure cocoa has the potential to reduce fatigue in people with relapsing and remitting multiple sclerosis (RRMS)

Crossref DOI link: https://doi.org/10.1186/s40814-018-0230-7

Published Online: 2018-01-23

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Coe, S.

Collett, J.

Izadi, H.

Wade, D. T.

Clegg, M.

Harrison, J. M.

Buckingham, E.

Cavey, A.

DeLuca, G. C.

Palace, J.

Dawes, H.
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Article History

Received: 2 August 2017

Accepted: 10 January 2018

First Online: 23 January 2018

Ethics approval and consent to participate

: This study was approved by the Solihull NRES Committee, West Midlands NHS ethics committee: 199515

: Not applicable.

: The gait measurement system and the smart watch software were developed by the research team (Dawes, Esser and Wade, and James and Amor, respectively), and both systems are in the process of being commercialised by the universities concerned.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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