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Article History

Received: 20 July 2025

Accepted: 3 November 2025

First Online: 20 January 2026

Declarations

:

: The trial received approval from the Danish Medicines Agency (2020110216) and The Regional Committees on Health Research Ethics for Southern Denmark (S-20200182). The trial was conducted in strict adherence to the principles outlined in the Helsinki Declaration and Good Clinical Practice guidelines.

: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

: Preliminary results from this study were presented at the first ever Joint Congress of the European Society for Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE) at the Bella Center in Copenhagen in may 2025.

: During the course of preparing this work, the authors used Chat GPT for the purpose of refining language, correcting spelling mistakes and grammar corrections. Following the use of this tool, the authors formally reviewed the content for its accuracy and edited it as necessary. The authors take full responsibility for all the content of this publication.

: The authors declare no competing interests.