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Article History

Received: 22 November 2024

Accepted: 12 March 2025

First Online: 31 March 2025

Declarations

:

: The study was submitted to the Ethics Committee of the IRCCS Carlo Besta Neurological Institute Foundation on 29 November 2022, and accepted on 18 January 2023 (“verbale n 11”). Informed consent was obtained from all subjects.

: Not applicable.

: CC, PP, PM declare no financial conflict of interest. SP declares research funding from Roche, MSD, GSK, Pfizer and AstraZeneca and honoraria for lectures and presentations from AstraZeneca, MSD, Roche, Pfizer, Novartis, and GSK. EB declares funds for research to the Mario Negri Institute from Roche, Astrazeneca and MSD. AS declares honoraria from GSK and MSD, consulting or advisory role for EISAI, MSD and GSK, speakers’ bureau for GSK and MSD, research funding from GSK, MSD and Mersana, and travel, accommodations and expenses from PharmaMar, GSK and MSD. PM is the president of “Nerina and Mario Mattioli Onlus Foundation”; SP is the president of MITO; AS is the coordinator of the group “New protocol” of MITO; EB is member of the scientific committee of MaNGO.