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Article History

Received: 18 June 2025

Accepted: 20 August 2025

First Online: 29 September 2025

Declarations

:

: All procedures performed in studies involving human participants were in accordance with the standards upheld by the Ethics Committee of the Second People’s Hospital of Changzhou and with those of the 1964 Helsinki Declaration and its later amendments for ethical research involving human subjects (Approval No. 2025[KY002-01]). All animal experiments were approved by the Ethics Committee of The Second People’s Hospital of Changzhou for the use of animals and conducted in accordance with the National Institutes of Health Laboratory Animal Care and Use Guidelines (Approval No. 2025[KY002-01]). The animal experiment complies with the ARRIVE guidelines and in accordance with the National Institutes of Health guide for the care and use of Laboratory animals.

: Written informed consent was obtained from a legally authorized representative(s) for anonymized patient information to be published in this article.

: The authors declare no competing interests.