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Article History

Received: 15 July 2024

Accepted: 30 December 2024

First Online: 3 March 2025

Declarations

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: The datasets generated during and analyzed during the current study are available from the corresponding author on reasonable request.

: Lauren Aleksunes is a member of the scientific advisory board of RenaSym® Simulations Plus. All other authors declare no conflicts of interest.

: This work was supported by a University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences (SSPPS) Associate Dean for Research (ADR) seed grant and the National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) [R01 GM123330]. Lauren Thompson was supported by predoctoral fellowships from the NIH National Center for Advancing Translational Sciences (NCATS)/Colorado Clinical and Translational Sciences Institute (CCTSI) [TL1 TR002533] and [UM1 TR004399] and NIH National Institute of Environmental Health Sciences (NIEHS) [T32 ES029074]. The University of Colorado Anschutz Medical Campus Pathology Shared Resource Research Histology Lab is supported in part by the NIH Cancer Center Support Grant [P30 CA046934].

: The authors thank Dr. Raphael Nemenoff at the University of Colorado Anschutz Medical Campus (UCAMC) for generously providing CMT167 cells to the research team. Additionally, the authors appreciate the contribution to this research made by E. Erin Smith, HTL(ASCP) of UCAMC Pathology Shared Resource, Research Histology Lab [Research Resource Identification (RRID): SCR_021994]. Contents are the authors’ sole responsibility and do not necessarily represent official NIH views.