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[225Ac]Ac- and [111In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-positive human breast cancer xenografts

Crossref DOI link: https://doi.org/10.1186/s41181-023-00208-0

Published Online: 2023-09-26

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kondo, Misaki

Cai, Zhongli

Chan, Conrad

Forkan, Nubaira

Reilly, Raymond M. https://orcid.org/0000-0003-1038-7993
Funding

Funding for this research was provided by:

Canadian Institutes of Health Research (462238)

Terry Fox Foundation (Strategic Training, Transdisciplinary Radiation Science for the 21st Century Scholarship)

Leslie Dan Faculty of Pharmacy, University of Toronto (Centre for Pharmaceutical Oncology Scholarship)
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Text and Data Mining valid from 2023-09-26

Version of Record valid from 2023-09-26
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Article History

Received: 14 June 2023

Accepted: 25 August 2023

First Online: 26 September 2023

Declarations

:

: This study was carried out in accordance with Canadian Council of Animal Care (CCAC) guidelines. The protocol (AUP6509.1) was approved by the Institutional Animal Care Committee of the University Health Network.

: Not applicable.

: The authors declare that they have no competing interests.

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