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It’s a match: use of the radionuclide theranostic pair 133La/225Ac for the radiopharmacological characterization of EGFR-targeted single-domain antibodies

Crossref DOI link: https://doi.org/10.1186/s41181-025-00354-7

Published Online: 2025-06-19

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Trommer, Johanna

Ullrich, Martin https://orcid.org/0000-0001-6104-6676
Reissig, Falco https://orcid.org/0000-0002-5203-0776
Brühlmann, Santiago Andres https://orcid.org/0000-0002-7840-6858
Nitt-Weber, Anne-Kathrin

Novy, Zbynek https://orcid.org/0000-0002-7716-2142
Hajduova, Katarina https://orcid.org/0009-0000-3078-0907
Kurfurstova, Daniela https://orcid.org/0000-0002-3175-3131
Hendrychova, Romana https://orcid.org/0000-0002-7272-6260
Bouchal, Jan https://orcid.org/0000-0003-4842-1720
Petrik, Milos https://orcid.org/0000-0003-1334-5916
Neuber, Christin https://orcid.org/0000-0002-0646-5808
Sihver, Wiebke https://orcid.org/0000-0002-2876-9925
Stadlbauer, Sven https://orcid.org/0000-0003-2276-5330
Pietzsch, Jens https://orcid.org/0000-0002-1610-1493
Kreller, Martin https://orcid.org/0000-0003-2424-3202
Kopka, Klaus https://orcid.org/0000-0003-4846-1271
Mamat, Constantin https://orcid.org/0000-0003-1906-3186
Zarschler, Kristof https://orcid.org/0000-0002-7571-4732
Funding

Funding for this research was provided by:

Helmholtz-Zentrum Dresden - Rossendorf e.V.
License Information

Text and Data Mining valid from 2025-06-19

Version of Record valid from 2025-06-19
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Article History

Received: 22 April 2025

Accepted: 29 May 2025

First Online: 19 June 2025

Change Date: 5 July 2025

Change Type: Update

Change Details: This article has been updated to amend the license information

Declarations

:

: Animal experiments using 133La-labeled compounds were carried out according to the guidelines of the German Regulations for Animal Welfare. The protocols were approved by the local Ethical Committee for Animal Experiments (license 25-5131/562/52). All animal experiments using 225Ac-labeled compounds were performed in accordance with appropriate legal norms (Czech Law No. 246/1992) and with the approval of the Ministry of Education, Youth and Sports (MSMT-35035/2019-3) and approval of the Ethical committee of Faculty of Medicine and Dentistry, Palacky University in Olomouc.

: Not applicable.

: The authors declare that they have no competing interests.

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