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Article History

Received: 27 September 2024

Accepted: 9 January 2025

First Online: 5 March 2025

Declarations

:

: The research project “Mechanistic Studies of Broadly Reactive Antibodies for the Treatment, Diagnosis, and Prevention of Pneumococcal Infection” has been reviewed by the Institutional Review Board (IRB) of the University of Mississippi Medical Center (Federalwide Assurance FWA#00003630) and has been determined to be exempt from formal review. The IRB concluded that the project meets the criteria for exemption as outlined in the U. S. Department of Health and Human Services Regulations for the Protection of Human Subjects, 45 CFR 46.102(l) because this project does not research involving human subjects. As such, no additional ethical review was required. All experiments involving animals were performed with prior approval of and in accordance with protocol 1584 which was reviewed and approved by the UMMC Animal Care Committee. UMMC laboratory animal facilities have been fully accredited by the American Association for Accreditation of Laboratory Animal Care. Procedures were performed according to the institutional policies, Animal Welfare Act, NIH guidelines, and American Veterinary Medical Association guidelines on euthanasia.

: N/A.

: N/A.

: The authors declare no competing interests.