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Article History

Received: 11 May 2021

Accepted: 5 October 2021

First Online: 27 October 2021

Declarations

:

: The use of data for this study was approved by the Cantonal Ethics commission of Bern (Kantonale Ethikkommission für die Forschung, KEK Bern) for the project with ID 2019-02151

: The manuscript does not contain any individual person’s data in any form.

: KC, ES, PB, SS, PB, JK, GD, ME, and GS declare that they have no conflict of interest with respect to this paper. LK´s institution (University Hospital Basel) has received in the last 3 years and used exclusively for research support: Steering committee, advisory board, and consultancy fees from: Actelion, Bayer HealthCare, Biogen, BMS, Genzyme, Glaxo Smith Kline, Janssen, Japan Tobacco, Merck, Novartis, Roche, Sanofi, Santhera, Shionogi, TG Therapeutics; Speaker fees from: Bayer HealthCare, Biogen, Merck, Novartis, Roche, and Sanofi; Support of educational activities from: Allergan, Bayer HealthCare, Biogen, CSL Behring, Desitin, Genzyme, Merck, Novartis, Roche, Pfizer, Sanofi, Shire, and Teva; License fees for Neurostatus products and grants from: Bayer HealthCare, Biogen, European Union, InnoSwiss, Merck, Novartis, Roche, Swiss MS Society, and Swiss National Research Foundation. CZ received honoraria for speaking and/or consulting fees and/or grants from Abbvie, Almirall, Biogen Idec, Celgene, Genzyme, Lilly, Merck, Novartis, Roche, and Teva Pharma.