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Authors
Williamson, Daniel
Vishnevetsky, Julia https://orcid.org/0009-0007-2807-1715
Ando, Masakazu
Xu, Yanqing
Ye, Xiaolan
Abel, Jessica L.
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Funding
Funding for this research was provided by:
AbbVie (AbbVie)
Ironwood Pharmaceuticals, Incorporated (Ironwood Pharmaceuticals, Incorporated)
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Article History
Received: 18 December 2024
Accepted: 26 August 2025
First Online: 20 November 2025
Declarations
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: This study received ethics approval from a central institutional review board (Western-Copernicus Group Institutional Review Board, tracking number 20191616) and local institutional review boards of the participating centers when necessary. Participants performed written, informed consent prior to study participation.
: Not applicable.
: JV, JLA, YX, and XY are employees of AbbVie and may hold shares and/or stock options in the company. MA is an employee of Ironwood Pharmaceuticals and may hold Ironwood Pharmaceutical shares and/or stock options. AbbVie and Ironwood sponsored the study; contributed to the design; participated in the collection, analysis, and interpretation of data; and participated in writing, reviewing, and approving the final version.
