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Article History

Received: 30 January 2020

Accepted: 3 June 2020

First Online: 19 September 2020

Ethics approval and consent to participate

: Prior to enrollment, patients were required to provide written informed consent to participate. Ethics approval was obtained from a central Research Ethics Board (IRB Service, Ontario, Canada) for private practices, and from respective Research Ethics Boards for institutional sites. The study was conducted in accordance with the Declaration of Helsinki.

: Not applicable.

: Proton Rahman has received consulting fees for Abbott, AbbVie, Amgen, BMS, Celgene, Janssen, Novartis, Pfizer and Roche; and received research grant from Janssen.Philip Baer has received consultant fees from AbbVie, Amgen, Janssen, Lilly, Novartis, Boehringer Ingelheim, Pfizer Inc., Sanofi-Genzyme and Merck and speaker’s fees from Amgen, Janssen, Abbvie, Pfizer Inc. and Lilly. Ed Keystone received funding for research from AbbVie, Amgen, Gilead Sciences, Lilly Pharmaceuticals, Merck, Pfizer Pharmaceuticals, PuraPharm, Sanofi; consulting agreements/advisory board membership from AbbVie, Amgen, AstraZeneca Pharma, Bristol-Myers Squibb Company, Celltrion, Myriad Autoimmune, F. Hoffmann-La Roche Inc., Genentech Inc., Gilead, Janssen Inc., Lilly Pharmaceuticals, Merck, Pfizer Pharmaceuticals, Sandoz, Sanofi-Genzyme, Samsung Bioepsis; speaker honoraria from Amgen, AbbVie, Bristol-Myers Squibb, Hoffmann-La Roche Inc., Janssen Inc., Merck, Pfizer Pharmaceuticals, Sanofi Genzyme and UCB. Denis Choquette has received consulting and speaking fees from Bristol-Myers Squibb, Abbvie, Amgen, Celgene, Genentech, Amgen, Pfzer, Roche and Novartis. Boulos Haraoui received advisory boards/consulting, and/or received research grants from AbbVie, Amgen, BMS, Celgene, Janssen, Eli Lilly, Merck, Novartis, UCB Pharma and Pfizer. Andrew Chow received advisory boards/consulting, and/or received research grants: AbbVie, Amgen, AstraZeneca, BMS, Celgene, Eli Lilly, Genzyme, GSK, Janssen, Merck, Novartis, Pfizer, Roche, Sanofi Aventis and UCB Pharma. Rafat Faraawi received consultant and speaker fees from Janssen Inc. Wojciech Olszynski received speaker/consultant fees for Amgen, Merck, Novartis, and Warner Chilcott. JPB: research grants, consulting fees, or speakers’ bureau fees from Abbott, Amgen, Bristol Myers Squibb, Eli Lilly, Merck, Novartis, Pfizer, Roche, Sanofi-Aventis, Servier, Takeda, and Warner Chilcott. John Kelsall reports personal fees from Abbott, AstraZeneca, BMS, Merck-Schering, Lilly, Pfizer, Wyeth, Roche, Takeda and UCB. Allen Lehman and Francois Nantel are employees of Janssen Inc. and are JNJ stockholders.