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A comparative study of the efficacy of single and double centrifuged platelet-rich plasma and placebo (normal saline injection) on pain, ROM, and physical function of patients with knee osteoarthritis: a double-blinded controlled randomized trial with a six-month follow-up

Crossref DOI link: https://doi.org/10.1186/s42358-026-00518-2

Published Online: 2026-01-27

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jahani, Paniz

Angoorani, Hooman

Moezy, Azar

Fazlinejad, Marzieh

Mazaherinezhad, Ali https://orcid.org/0000-0002-2771-2994
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Text and Data Mining valid from 2026-01-27

Version of Record valid from 2026-02-18
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Article History

Received: 26 May 2025

Accepted: 9 January 2026

First Online: 27 January 2026

Declarations

:

: This study was approved by the Ethics Committee of Iran University of Medical Sciences (Approval Code: IR.IUMS.FMD.REC.1399.611). All procedures were conducted in accordance with the Declaration of Helsinki. Written informed consent was obtained from all participants prior to enrollment.

: The authors declare no competing interests.

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