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Article History

Received: 20 August 2021

Accepted: 5 November 2021

First Online: 27 December 2021

Declarations

:

: The study was conducted in accordance with the Declaration of Helsinki of the World Medical Association and approval was obtained from the local ethics committees (ethics committees of the medical associations of Hamburg, Schleswig–Holstein, Niedersachsen, approval: PV5483). Consent to participate in the study was given by all included participants.

: Consent to publish the results was given by all included participants.

: T.I., S.W., G.Bi., E.S., C.B., G.Be., A.M., A.N., K.O., O.P., M.P., J.S have no competing interest. C.G. reports personal fees from Amgen, Bayer Vital, Bristol-Myers Squibb, Boehringer Ingelheim, Sanofi Aventis, Abbott, and Prediction Biosciences outside the submitted work. G.T. reports receiving consulting fees from Acandis, grant support, and lecture fees from Bayer, Boehringer Ingelheim, Bristol-Myers Squibb/Pfizer, and Daiichi Sankyo, and consulting fees and lecture fees from Stryker outside the submitted work.