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Article History

Received: 10 February 2023

Accepted: 4 May 2023

First Online: 1 June 2023

Declarations

:

: The MonDAFIS study was approved by the Ethics Committee of participating study sites, first by the Charité Ethics Committee, Berlin, Germany (EA2_033_14). All study patients gave written informed consent.

: Not applicable.

: ST, UG, CK, MJUQ, and MO report no conflict of interests outside the submitted work. PK receives research support for basic, translational, and clinical research projects from European Union, British Heart Foundation, Leducq Foundation, Medical Research Council (UK), and German Centre for Cardiovascular Research, from several drug and device companies active in atrial fibrillation, and has received honoraria from several such companies in the past. PK is listed as inventor on two patents held by University of Birmingham (Atrial Fibrillation Therapy WO 2015140571, Markers for Atrial Fibrillation WO 2016012783). GT has received speaker´s honoraria or consulting fees from Acandis, Bayer Healthcare, Boehringer Ingelheim, Covidien, Bristol-Myers-Squibb, Portola, Stryker and Pfizer, and is a section editor of Neurological Research and Practice. DGN has received speaker's and consulting fees from Astra Zeneca, Bayer, Boehringer Ingelheim, Bristol-Myers-Squibb, Pfizer, an Daiichi Sankyo. JR has received speaker´s honoraria and consulting fees from Bayer, Boehringer Ingelheim, Bristol-Myers-Squibb, Pfizer, Daiichi Sankyo, Alexion and Astra Zeneca. UL reports honoraria/reimbursements for lectures, participation in studies, scientific cooperations (with Saarland University), consulting, travel, support (of colleagues) or support of scientific meetings by Amgen, Bayer, Boehringer-Ingelheim, Daiichi-Sankyo, MSD, Sanofi, Servier outside the submitted work. RV reports grants, personal fees and other from Bayer, grants from Boehringer, grants and personal fees from BMS, grants from Daiichi Sankyo, grants from Medtronic, personal fees from Javelin, grants from Biogen, grants and personal fees from Pfizer, personal fees from Abbott, personal fees from Astra Zeneca, other from Novartis, outside the submitted work, and is an editorial board member of Neurological Research and Practice. RV is an investigator of Imperial BRC and partially funded by the European Union's Horizon 2020 research and innovation programme under grant agreement No. 754517 (PRESTIGE-AF). PUH reports grants from Charité - Universitätsmedizin Berlin during study conduct (within MonDAFIS for biometry; member scientific board); research grants from German Ministry of Research and Education, German Research Foundation, Bavarian State, European Union, German Cancer Aid, German Parkinson Society, University Hospital Würzburg, German Heart Foundation, Federal Joint Committee (G-BA) within the Innovationsfonds, University Hospital Heidelberg (within RASUNOA-prime; supported by an unrestricted research grant to the University Hospital Heidelberg from Bayer, BMS, Boehringer-Ingelheim, Daiichi Sankyo), University Göttingen (within FIND-AF randomized; supported by an unrestricted research grant to the University Göttingen from Boehringer-Ingelheim), outside the submitted work. ME reports grants from Bayer and fees paid to the Charité from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Bristol-Myers-Squibb, Covidien, Daiichi Sankyo, Glaxo Smith Kline, Novartis, Pfizer, and Sanofi, and is an editorial board member of Neurological Research and Practice. KGH reports speaker´s honoraria, consulting fees, lecture honoraria and/or study grants from Abbott, Alexion, Amarin, AstraZeneca, Bayer Healthcare, Sanofi, Boehringer Ingelheim, Boston Scientific, Daiichi Sankyo, Pfizer, Bristol-Myers Squibb, Biotronik, Medtronic, Novartis, Portola, Getemed AG, Premier Research, W.L. Gore and Associates, SUN Pharma and Edwards Lifesciences.