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Impact of combined CYP3A4 and CYP3A5 single- nucleotide polymorphisms on tacrolimus exposure and acute rejection in Egyptian pediatric kidney transplant recipients: single center experience

Crossref DOI link: https://doi.org/10.1186/s43054-025-00416-0

Published Online: 2025-09-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Fadel, Fatina I.

M. Salah, Doaa

Gamal Elshabrawy, Eman

Sobh, Ali

Mohamed Mossad, Yossef

Abdelbaset Bakr, Ashraf

Abobakr Abd Alazem, Eman
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Article History

Received: 1 May 2025

Accepted: 8 August 2025

First Online: 4 September 2025

Declarations

:

: The study protocol was approved by Pediatric Nephrology Unit, Pediatric Department, Faculty of Medicine, Cairo University (N-169–2024) and Mansoura Faculty of Medicine Institutional Research Board (MD.19.11.254).Informed consent was obtained and documented for all participants. All procedures used in this study adhere to the tenets of the Declaration of Helsinki 1967.

: The authors declare no competing interests.

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