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Article History

Received: 16 November 2024

Accepted: 14 June 2025

First Online: 28 July 2025

Declarations

:

: Approval was obtained for this prospective study from the institutional review board and the Research Ethics Committee of faculty of medicine, Alexandria University Hospital in Egypt on 2021, and informed consent was obtained from the enrolled participants, reference number: 0201587, IRB number 00012098. All study procedures have been carried out adhering to the tenets of the Declaration of Helsinki regarding research involving human subjects.

: Not applicable.

: No datasets were generated or analysed during the current study.

: The authors declare no competing interests.

: No sources of funding (not applicable).

: BA designed the study, collected the data, carried out statistical analysis and wrote the manuscript. HH and EB interpreted the MR images, edited the manuscript and revised the sequence alignment. AMA and MAH edited the manuscript and revised the sequence alignment. All authors read and approved the final manuscript.

: Not applicable