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Allosteric modulation of laeviganoid-based clerodane diterpenes derivatives in muscarinic acetylcholine M1 receptor against tinnitus: a structure-based virtual screening approach

Crossref DOI link: https://doi.org/10.1186/s43094-025-00783-w

Published Online: 2025-03-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Silva, Jacilene

da Rocha, Matheus Nunes https://orcid.org/0000-0002-0929-4565
de Oliveira, Victor Moreira

Roberto, Caio Henrique Alexandre

Lúcio, Francisco Nithael Melo

Marinho, Márcia Machado

dos Santos, Hélcio Silva

Marinho, Emmanuel Silva
Funding

Funding for this research was provided by:

Conselho Nacional de Desenvolvimento Científico e Tecnológico (306008/2022-0, DCT-0182-00048.02.00/21)

Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico (04879791/2022)
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Text and Data Mining valid from 2025-03-11

Version of Record valid from 2025-03-11
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Article History

Received: 22 February 2024

Accepted: 22 February 2025

First Online: 11 March 2025

Declarations

:

: No animal experiments were performed in this work.

: Not applicable.

: The authors declare that they have no competing interests.

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