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In silico and in vivo study: chamazulene and/or cinnamic acid modulate IRS2/GLUT4, HNF4α, GLUT2, redox system, DNA damage, and lipid profile signifying their potential antidiabetic effect

Crossref DOI link: https://doi.org/10.1186/s43094-025-00880-w

Published Online: 2025-10-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Shafey, Heba I. https://orcid.org/0000-0002-2836-029X
Batawi, Ashwaq H. https://orcid.org/0000-0003-3932-1904
Shalaby, Mohamed B. https://orcid.org/0000-0002-3006-393X
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Text and Data Mining valid from 2025-10-13

Version of Record valid from 2025-10-13
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Article History

Received: 13 June 2025

Accepted: 8 September 2025

First Online: 13 October 2025

Declarations

:

: The General Organization of Teaching Hospitals and Institutes Ethics Committee (no: IME00090) approved the use of anesthetics and the handling of animals.

: The authors state that they agree for the Future Journal of Pharmaceutical Sciences to publish their work.

: There is no conflict of interest declared by the authors.

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