Zhou, Jinge
Wang, Chen
Wu, Yan
Zhao, Baoxin
Yang, Yun
Ye, Tianxi
Zhang, Kaiyue
Li, Fangxu
Hu, Jiang
Zhang, Kai
Liu, Fang
Wang, Weiqi
Wang, Chunhua
Wang, Zefeng
Chuai, Xia
Chiu, Sandra
Funding for this research was provided by:
Strategic Priority Research Program of the Chinese Academy of Sciences (XDB0490000)
National Key Research and Development Program of China (2022YFC2304102)
USTC Research Funds of the Double First-Class Initiative (YD9100002040)
Article History
Received: 9 October 2025
Revised: 9 May 2026
Accepted: 11 May 2026
First Online: 28 May 2026
Declarations
:
: All animal experiments were reviewed and approved by the Institutional Animal Care and Use Committee (IACUC) of the Wuhan Institute of Virology (Chinese Academy of Sciences, approval number WIVA45202203). All experimental procedures were conducted in strict compliance with Chinese Laboratory Animal Regulations and the guidelines on Laboratory Animal Environment and Housing Facilities Requirements .All experiments with live MPXV were carried out in the BSL-3 facilities of the Wuhan Institute of Virology, Chinese Academy of Sciences, with approval number NBL3-2024069.
: Not applicable.
: Yun Yang, Jiang Hu, Kai Zhang, and Fang Liu are employees of CirCode. Zefeng Wang is an advisor to CirCode. Zefeng Wang and Yun Yang are cofounders of CirCode Biomed. There is one unpublished patent application directed to the subject matter of the paper. Other authors have no conflicts of interest.