Ha, Hyun-Yee
Han, Seung-Hyeon
Cho, Seung-Hun
Article History
Received: 29 March 2025
Accepted: 6 July 2025
First Online: 22 August 2025
Change Date: 5 October 2025
Change Type: Update
Change Details: The original online version of this article was revised: In this article typos have been found and corrected:
Change Details: 1. LCN2 labeling error
Change Details: Location: Last sentence of Abstract Original: “LNC2” → Correction: “LCN2” → This part will be corrected to “LCN2.”
Change Details: 2. Western blot unit error
Change Details: Location: Methods, Western blot (p.4) Original: “40 mg per lane” → Correction: “40 µg per lane” → This part will be corrected to “40 µg per lane.”
Change Details: 3. Typos NanoDrap → NanoDrop Sigma-Aldirich → Sigma-Aldrich → The typos will be corrected as indicated.
Change Details: 4. Reference errors
Change Details: Ref #37: Journal and DOI mismatch (Cell Reports vs. eNeuro DOI) → Correct journal title: Cell Reports DOI: 10.1016/j.celrep.2021.109638 Ref #48: Title “Rregulates” → “Regulates” → Corrected to “Regulates.” Ref #51: Journal title “Biolo Pharma Bull.” → “Biol Pharm Bull.” → Corrected to “Biol Pharm Bull.”
Change Details: 5. Abbreviation table
Change Details: “PC-3: Protects prostate cancer-3” → “PC-3: prostate cancer cell line” → Since PC-3 is the proper name of a cell line, it will be deleted from the list of abbreviations. → In addition, the relevant text in Discussion, Ref #55, will be corrected as follows: “protects prostate cancer-3 (PC-3) cells from apoptosis(55).” → Corrected to: “protects human prostate cancer cell line PC-3 from apoptosis(55).”
Change Details: 2. Clarification Requests
Change Details: 1. RT-PCR primer sequence duplication
Change Details: Location: Table 1 Issue: IL-1β (F/R) and IL-6 (F/R) primer sequences are identical
Change Details: Request: Provide actual primer sequences used, Tm, product size, supplier, and original data verification → Upon review, we confirmed that Table 1 incorrectly listed the RT-PCR primer sequences: the IL-1β (F/R) primers were mistakenly recorded as the IL-6 (F/R) primers during the editing process. As a result, the RT-PCR data for IL-1β included in Table 1 do not accurately represent the gene expression. To ensure academic integrity, we have determined that it is appropriate to delete the IL-1β (F/R) data in Table 1. The mentions of IL-1β in Discussion (Refs #46, #47, #52) are based on cited references and not on experimental results of this study; therefore, they need not be deleted. Importantly, the main conclusions of this study are sufficiently supported by the IL-6 and other inflammation-related indicators. Thus, the deletion of IL-1β data does not affect the essential interpretations or conclusions of the article.
Change Details: 2. STZ injection coordinate inconsistency
Change Details: Text: AP −0.4, DV −2.3 / Fig.1: AP −0.5, DV −2.8
Change Details: Request: Confirm actual coordinates, reference atlas, and surgical records → This was a typographical error in the text. The correct coordinates are those in Fig.1: AP −0.5, DV −2.8.
Change Details: 3. Aβ data labeling inconsistency
Change Details: Fig.9 caption: “absorbance 450 nm” / y-axis: “Aβ (ng/ml)”
Change Details: Request: Clarify actual analysis method (absorbance vs. ELISA quantification) and unify units/axis/caption → The correction should be as follows: Y-axis: “Amyloid β” Caption: “The Amyloid β (Aβ) protein level measured by ELISA at 450 nm absorbance.”
Change Details: 4. Drug classification sentence error
Change Details: Location: Discussion (p.10)
Change Details: Original: “acetylcholinesterase inhibitors (N-methyl-D-aspartate antagonists)”
Change Details: Request: Address confusion between donepezil (AChE inhibitor) and memantine (NMDA antagonist) → provide intended meaning and corrected sentence → As pointed out, the phrase “(N-methyl-D-aspartate antagonists)” was inappropriately included. The parenthetical expression will be deleted.
Change Date: 17 October 2025
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1186/s44424-025-00027-x
Declarations
:
: The authors declare no competing interests.
: This research was approved by the Institutional animal care and use committee, Department of Neuropsychiatry in Korean Medicine, Kyung Hee University Medical Center, Seoul, Korea.
: This research was approved by the Institutional animal care and use committee, Department of Neuropsychiatry in Korean Medicine, Kyung Hee University Medical Center, Seoul, Korea.
: Not applicable.