Funding for this research was provided by:
Helse Sør-Øst RHF (2016037)
Oslo University Hospital, Norway
Received: 18 September 2019
Accepted: 18 December 2019
First Online: 31 December 2019
Ethics approval and consent to participate
: All parts of the study were approved by the Regional committee for medical and health research ethics (2010/2014 REK Sør-Øst D), in accordance with the Declaration of Helsinki. Patients were enrolled on admission, and written informed consent was obtained as soon as possible. A temporary written consent from the closest relative was obtained when patients were unable to consent. All material was destroyed if patients or relatives did not consent. The Regional committee for medical and health research ethics approved the use of biological material from patients who died before a fully informed consent could be obtained, and the use of written information with the possibility for withdrawal for patients who were transferred to other hospitals or discharged before consent could be obtained. All those patients were checked against the Norwegian national biological research reservation registry before final inclusion.
: Not applicable.
: The authors declare that they have no competing interests.