Funding for this research was provided by:
National Institutes of Health (HL109618, HL098329, AI117397, K08HL136847)
Received: 30 December 2019
Accepted: 27 April 2020
First Online: 27 May 2020
Ethics approval and consent to participate
: This study was conducted in accordance with the amended Declaration of Helsinki. The University of Virginia Institutional Review Board approved the protocol, and written informed consent was obtained from all patients or designated health care proxy (UVA IRB-HSR# 14159). For the animal studies, all mice were maintained under pathogen-free conditions throughout the experiments and were cared for according to methods approved by the American Association for the Accreditation of Laboratory Animal Care. All live animal experiments and procedures were performed with the approval of the Institutional Animal Care and Use Committee at the University of Virginia.
: Not applicable.
: None to declare.