Article History

Received: 16 December 2021

Accepted: 27 January 2022

First Online: 9 April 2022

Change Date: 28 April 2022

Change Type: Correction

Change Details: A Correction to this paper has been published:

Change Details: https://doi.org/10.1186/s10194-022-01422-y

Change Date: 7 June 2022

Change Type: Correction

Change Details: A Correction to this paper has been published:

Change Details: https://doi.org/10.1186/s10194-022-01434-8

Declarations

:

: All patients provided written informed consent. The study was approved by IRCCS San Raffaele Rome Ethical Committee n RP 19/26, mutually recognized by the other local ethical committees.

: Piero Barbanti received travel grants, honoraria for advisory boards, speaker panels or clinical investigation studies from Alder, Allergan, Angelini, Assosalute, Bayer, ElectroCore, Eli-Lilly, GSK, Lundbeck, Lusofarmaco, 1MED, MSD, New Penta, Noema Pharma, Novartis, Stx-Med, Teva, Visufarma, Zambon.Cinzia Aurilia received travel grants from FB-Health, Lusofarmaco, Almirall, Eli-Lilly Novartis and Teva;Gabriella Egeo received travel grants and honoraria from Eli-Lilly, Novartis, New Penta and Ecupharma;Florindo d'Onofrio received travel grant, honoraria as a speaker or for partecipating in advisory boards from Novartis, Teva, Neopharmed Gentili, Qbgroup srl, K link srl and Eli-Lilly.Maria Albanese received travel grants and honoraria from Novartis, Teva, Eli-Lilly and Lundbeck.Ilaria Cetta have no disclosures to declare.Paola Di Fiore received honoraria as a speaker or for participating in advisory boards from Novartis and Teva.Maurizio Zucco received travel grants and honoraria from Novartis.Massimo Filippi is Editor-in-Chief of the Journal of Neurology; received compensation for consulting services and/or speaking activities from Bayer, Biogen Idec, Merck-Serono, Novartis, Roche, Sanofi Genzyme, Takeda, and Teva Pharmaceutical Industries; and receives research support from Biogen Idec, Merck-Serono, Novartis, Roche, Teva Pharmaceutical Industries, Italian Ministry of Health, Fondazione Italiana Sclerosi Multipla, and ARiSLA (Fondazione Italiana di Ricerca per la SLA).Francesco Bono received honoraria as a speaker or for participating in advisory boards from Teva, Novartis and Ipsen.Claudia Altamura received travel grants or honoraria for speaker panels from Eli-Lilly, Novartis, Teva, Lusofarmaco, Almirall, Laborest.S. Proietti have no disclosures to declare.S. Bonassi have no disclosures to declare.Fabrizio Vernieri received travel grants, honoraria for advisory boards, speaker panels or clinical investigation studies from Allergan, Eli-Lilly, Novartis, Teva, Amgen, Angelini and Lundbeck.