Funding for this research was provided by:
Wellcome Trust (203128/Z/16/Z)
Biotechnology and Biological Sciences Research Council (BB/L024551/1)
Received: 6 November 2019
Accepted: 11 June 2020
First Online: 17 June 2020
Ethics approval and consent to participate
: Human patients were consented under protocol REC#14/NW/0260 under the University of Manchester Health Research Authority.
: Not applicable.
: The authors declare that they have no competing interests.