Thorne, Adam M.
Huang, Honglei
O‘Brien, Darragh P.
Eijken, Marco
Krogstrup, Nicoline Valentina http://orcid.org/0000-0001-7144-730X
Norregaard, Rikke
Møller, Bjarne
Ploeg, Rutger J.
Jespersen, Bente
Kessler, Benedikt M. http://orcid.org/0000-0002-8160-2446
Funding for this research was provided by:
The Danish Council for Independent Research Medical Sciences
National Institute of Health Research
Article History
Received: 12 January 2020
Accepted: 10 October 2020
First Online: 2 November 2020
Ethics approval and consent to participate
: Patient samples were taken from the CONTEXT clinical trial [CitationRef removed]. The trial protocol, including consent form and participant information, is approved by the national agencies of Denmark, Sweden and The Netherlands, including the local ethical committees (Denmark: 31894 November 2011, Netherlands 2013/141) and the data protection agencies (Denmark: J.nr. 2011-41-6477; Sweden: Patient Data Act 2008:355; The Netherlands: Dutch Data Protection Act, derived from Directive 95/46/EC). All minor and major amendments to the protocol required approval by the appropriate ethical committees. A data monitoring committee was not required. The trial was conducted in accordance with the ethical principles of the Declaration of Helsinki and the Declaration of Istanbul.
: All authors have seen the manuscript and given their consent for publication.
: The authors declare no competing financial interests in the context of this study.