Funding for this research was provided by:
Bundesministerium für Bildung und Forschung (01ZX1302, 01KU1505A, 01KU1001A, 01KU1505E)
Received: 4 December 2018
Accepted: 26 April 2019
First Online: 28 May 2019
Ethics approval and consent to participate
: This study was conducted in accordance with the Declaration of Helsinki. Informed consent from all patients were obtained in written form as outlined in the original sequencing studies [CitationRef removed–CitationRef removed, CitationRef removed]. Positive ethical votes were granted respectively by the Ethics Committee of the Medical Faculty of Heidelberg [CitationRef removed, CitationRef removed, CitationRef removed] and the Ethics Committee of Heidelberg University [CitationRef removed].
: Not applicable.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.