Choi, Jaeyong
Lee, Woochan
Yoon, Jung-Ki
Choi, Sun Mi
Lee, Chang-Hoon
Moon, Hyeong-Gon
Cho, Sukki
Chung, Jin-Haeng
Yang, Han-Kwang
Kim, Jong-Il
Funding for this research was provided by:
National Research Foundation of Korea (2020R1A2C3012524)
Article History
Received: 11 July 2021
Accepted: 28 March 2022
First Online: 2 May 2022
Declarations
:
: All studies were conducted in accordance with the Declaration of Helsinki and the Guidelines for Good Clinical Practice and performed after receiving written informed consent obtained from each participant and/or their legal representative, as appropriate. The institutional review board of the Seoul National University Hospital granted permission to perform this study (2008-065-1148, 1909-110-1066, 1805-151-948, and 1402-054-555). All animal studies were carried out in accordance with ARRIVE guidelines and other relevant guidelines/regulations. Mouse normal islet and intestine tissues were obtained from a 12-week-old female C57BL/6 mouse. Patient derived xenograft model was established with female immunodeficient CIEA NOG mouse. The Institute of Laboratory Animal Resources Seoul National University approve all animal experiment in this study (19-0096-S1A1(2), SNU-190401-5-7, SNU-200707-1-1).
: Not applicable.
: The authors declare that they have no competing interests.