Holt, Ian
Fuller, Heidi R.
Schindler, Roland F. R.
Shirran, Sally L.
Brand, Thomas
Morris, Glenn E.
Funding for this research was provided by:
British Heart Foundation (PG/16/68/31991, PG/19/13/34247)
Orthopaedic Institute Ltd., Oswestry (RPG141 and RPG189)
Article History
Received: 8 July 2020
Accepted: 18 November 2020
First Online: 1 December 2020
Ethics approval and consent to participate
: This study has been approved by the RJAH Orthopaedic Hospital Research Committee. All human tissue studies complied with the UK Human Tissue Act (2006). Human biopsies were obtained following written informed consent using protocols approved by RJAH Orthopaedic Hospital, Oswestry and Imperial College, London. Muscle biopsy for immortalisation of myoblasts was obtained with written informed consent in accordance with European recommendations and French legislation. All animal procedures were performed with approval of the Keele University Animal Welfare and Ethical Review Body and conducted under the licensed authority of the UK Home Office.
: Not applicable.
: The authors declare that they have no competing interests.