Funding for this research was provided by:
CAMS Initiative for Innovative Medicine, China (CAMS-I2M-1-019)
Medical reserve talents of Yunnan Provincial Health and Family Planning, China (H-201620)
Major science and technology special projects of Yunnan Province (2017ZF020, 2014HB066)
Central Research Institutes of Basic Research and Public Service Special Operations, China (2016ZX310180-6)
Received: 7 August 2017
Accepted: 12 January 2018
First Online: 25 January 2018
: The animal experiments were reviewed and approved by the Experimental Animal Ethics Committee of the Institute of Medical Biology, Chinese Academy of Medical Sciences for animal welfare (Approval number: YISHENGLUNZI  12).
: Not applicable.
: All authors have completed the Unified Competing Interest form and declare that they have no competing interests. The sponsors and funders of the present study played no role in the study design, data or sample collection, data processing, or drafting of the manuscript. The corresponding authors had full access to all data generated in the present study and assume full responsibility for the final submission of this manuscript for publication.