Funding for this research was provided by:
National Institutes of Health (R01 DA040391)
Received: 21 June 2020
Accepted: 26 October 2020
First Online: 11 November 2020
Ethics approval and consent to participate
: Plasma samples in the test cohort were obtained from the Chicago site of the Multicenter AIDS Cohort Study (MACS). All participants were enrolled with written informed consent and IRB approval at Northwestern University Feinberg School of Medicine. Plasma from HIV-positive subjects in the validation cohort were obtained from National NeuroAIDS Tissue Consortium (NNTC) and healthy control plasma samples were from Bioreclamation IVT, with written informed consent from all participants and IRB approval at each NNTC study site (Manhattan HIV Brain Bank, National Neurological AIDS Bank, California NeuroAIDS Tissue Network, Texas NeuroAIDS Research Center) and Dana-Farber Cancer Institute, respectively.
: Not applicable.
: The authors declare that they have no competing interests.