Funding for this research was provided by:
National Natural Science Foundation of China (81570485, 81770538)
Key Technology Research and Development Program of Shandong (2017CXGC1215)
Received: 19 January 2020
Accepted: 3 June 2020
First Online: 17 June 2020
Ethics approval and consent to participate
: The study was performed in accordance of Declaration of Helsinki and approved by the ethics committee in Qilu Hospital of Shandong University. All of subjects gave written informed consent prior to recruitment and sample collection.
: Not applicable.
: The authors declare that they have no competing interests.