Funding for this research was provided by:
Biotechnology and Biological Sciences Research Council (BB/S506679/1, BB/R012490/1, BBS/E/F/000PR10356, BB/R012504/1, BBS/E/F/000PR10348, BBS/E/F/000PR10349, BBS/E/F/000PR10351, BBS/E/F/000PR10352, BB/M011216/1, BBS/E/F/000PR10355)
Received: 12 March 2021
Accepted: 18 August 2021
First Online: 6 September 2021
: Human tissue samples were accessed in accordance with the research protocol approved by the Faculty of Medicine and Health Sciences Research Ethics Committee (FMH REC) of the University of East Anglia (UEA) (FMH Reference 2013/2014–67 HT and R204719) and registered at ExternalRef removed (NCT03679533 and NCT02188238). These samples were obtained via the NRP Biorepository (Human Tissue Authority-licensed tissue bank, License number 11,208) under the ethics approval granted by the National Health Service Health Research Authority (NHS HRA) (East of England-Cambridge East Research Ethics Committee, REC Ref 19/EE/0089; IRAS number 259,062). An additional stool sample was accessed through a study approved by the Quadram Institute Bioscience, Human Research Governance committee (IFR01/2015), and London - Westminster Research Ethics Committee (15/LO/2169). The latter trial is registered at ExternalRef removed (NCT02653001).
: Not applicable.
: The authors declare that there are no conflicts of interest.