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Article History

Received: 22 September 2019

Accepted: 15 June 2020

First Online: 27 June 2020

Ethics approval and consent to participate

: This study was approved by the ethics committee of Huashan Hospital, Fudan University, Shanghai, China (approval number: KY2018–232) and registered atExternalRef removed(registration number: CHiCTR1800016621). All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Written informed consent was obtained from the patents of aged 16 and older. For participants under 16 years old of age, a parent or guardian also signed in the consent form.

: Not Applicable.

: The authors declare that there are no conflicts of interest in this work.