Horrow, Jay C.
Li, Wen
Blobner, Manfred
Lombard, John
Speek, Marcel
DeAngelis, Matthew
Herring, W. Joseph http://orcid.org/0000-0001-9133-031X
Funding for this research was provided by:
Merck (N/A)
Article History
Received: 31 July 2020
Accepted: 11 February 2021
First Online: 27 February 2021
Ethics approval and consent to participate
: Ethics committees at each site approved this randomized, active comparator-controlled, parallel-group, double-blind study (ExternalRef removed: ExternalRef removed), conducted at 25 sites in 5 countries from January, 2018 to January, 2019. The independent ethics committees were: Ethik-Kommission Der Stadt Wien, Universitair Ziekenhuis Antwerpen Ethisch Comite, De Videnskabsetiske Komiteer for Region Hovedstaden, Ethik-Kommission der Landesaerztekammer Baden-Wuerttemberg, University of California Davis Medical Center IRB, Western Institutional Review Board, Zablocki VA Medical Center IRB, Mission Health IRB, Copernicus Group Independent Review Board, Cleveland Clinic Institutional Review Board, Vanderbilt Human Research Protection Program, University of Kansas Medical Center IRB, and University of Missouri-Columbia (MU) Institutional Review Board. All patients provided written, informed consent.
: Not applicable.
: JCH is a former employee of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. WL, JL, MS, MD, and WJH are employees of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. MB received grants and personal fees from MSD, Haar, Germany, personal fees from GrĂ¼nenthal, Aachen, Germany, and personal fees from GE Healthcare, Helsinki, Finland. JCH is currently Clinical Professor of Anesthesiology & Critical Care Medicine at the University of Pennsylvania, Philadelphia, PA, USA.