Received: 4 November 2020
Accepted: 10 February 2021
First Online: 20 February 2021
Ethics approval and consent to participate
: The study received approval by an independent Ethics Committee (Ethics Committee, Istituto Ortopedico Rizzoli di Bologna - IRCCS, Bologna on 23rd of February 2015). All study patients signed informed consent. All methods were carried out in accordance with relevant guidelines and regulations (Declaration of Helsinki).
: The manuscript does not contain any individual person’s data in any form.
: Daniela Ghisi has participated as a medical consultant to a scientific advice with Sintetica S.A. The other authors have no competing interest to declare.