Funding for this research was provided by:
Canadian Institutes of Health Research (200804MOP-190260-GSH-CFAC-40513)
Heart and Stroke Foundations of Quebec, Nova Scotia, Ontario, Alberta, British Columbia and Yukon, and Canada
Received: 13 March 2017
Accepted: 26 January 2018
First Online: 6 February 2018
Ethics approval and consent to participate
: Ethics approval was obtained from the McGill University Health Centre and from the hospital ethics review boards at each participating centre. In the United States, ethics approval was obtained from The Mary Imogene Bassett Institutional Research Board (Cooperstown, New York). In Switzerland, ethics approval was obtained from Commission cantonale d’éthique de la recherche sur l’être humain (Lausanne). Each participant included in the study provided written informed consent to participate.
: Not applicable
: All authors declare that they have no competing interests.
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