Funding for this research was provided by:
FP7 Ideas: European Research Council
Chief Scientist Office (PCL 17/07)
Wellcome Trust (WT085664)
Received: 12 October 2017
Accepted: 2 February 2018
First Online: 13 February 2018
Ethics approval and consent to participate
: The study protocols were approved by The East of Scotland Research Ethics Committee, and were conducted in accordance with the Declaration of Helsinki. All volunteers who participated in this study provided written informed consent. Informed consent was obtained from each patient and the study protocol conformed to the ethical guidelines of the 1975 Declaration of Helsinki.
: Not applicable.
: The authors declare that they have no competing interests.
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