Received: 10 February 2019
Accepted: 3 May 2019
First Online: 15 May 2019
Ethics approval and consent to participate
: The study was approved by the ethics committee of the Otto-von-Guericke University Magdeburg on Mai 4th, 2015 (approval number 10/15). All patients gave their informed written consent before enrollment in the study. The Study was registered on 07.07.2016 in the German Clinical Trials Register (<i>DRKS; ID: DRKS00010768</i>).
: Not applicable.
: The authors declare that they have no competing interests.
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