Funding for this research was provided by:
H2020 European Research Council (720834, 720834)
Received: 5 June 2019
Accepted: 26 September 2019
First Online: 15 October 2019
Ethics approval and consent to participate
: The experiments were performed either at the Section for Surgical Research, Department of Experimental Surgery or at the Institute for Biomedical Research of the Medical University of Graz (Auenbruggerplatz 15, 8036 Graz, Austria). The experimental protocols were approved by the local bioethics committee of Vienna, Austria (Austrian Committee for Animal Trials, in German “Tierversuchskommission”, BMWF-66.010/0091-II/3b/2013, BMWF-66.010/0033-II/10b/2008, BMWF-66.010/0103-II/10b/2009, BMWF-66.010/0108-II/3b/2010), and conforms to the “European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes” (Council of Europe No 123, Strasbourg 1985).
: Not applicable.
: None of the authors reports a relationship with industry and other relevant entities – financial or otherwise – that might pose a conflict of interest in connection with the submitted article. The following authors report financial activities outside the submitted work: DA reports no conflict of interest. AF reports no conflict of interest. BP reports having received consultancy and lecture honoraria from Bayer, Daiichi Sankyo, MSD, Novartis, Sanofi-Aventis, Stealth Peptides and Vifor Pharma; and editor honoraria from the Journal of the American College of Cardiology. HP reports no conflict of interest. AA reports no conflict of interest. MM reports no conflict of interest. DZ reports no conflicts of interest. KPK reports having received lecture honoraria from Bristol-Myers Squibb.